Cellular findings show Telomir-Zn modulates intracellular metal balance linked to oxidative stress, mitochondrial ...

The role of epigenetic mechanisms, such as DNA or RNA methylation, histone modifications, nucleosome changes, and non-coding RNAs in cancer has gained increasing interest in recent studies. The ...

Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and ...

This review is designed by Dr. Yinglan Zhao and written by her PhD students Dr. Lei Tao and Yue Zhou (Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University).

During the process of metastasis, tumor cells inevitably encounter the stimulation of various oxidative stressors, resulting in the fluctuation of intracellular reactive oxygen species (ROS) levels.

As the climate crisis intensifies, traditional genetic breeding alone may not keep pace with the rapid shifts in environmental stressors. While the ...

Determining the genetic and epigenetic factors that influence brain folding is the objective of the latest study co-led by the Neurogenesis and Cortical Expansion laboratory, directed by researcher ...

Researchers have revealed the mechanism of the drug valemetostat shown to be effective in treating certain types of cancer by targeting a protein modification (histone methylation) silencing the ...

The next frontier in data-driven skin health ...

The observed Telomir-Zn-associated increase in intracellular zinc, coupled with a reduction of labile iron, is consistent with a proposed intracellular mechanism by which modulation of metal ...