Mitochondria play a key role in apoptosis due to their capacity to release potentially lethal proteins. One of these latent death factors is cytochrome c, which can stimulate the proteolytic ...
HtrA2/Omi ? a mammalian mitochondrial serine protease ? has an important role in apoptosis. It was identified because it binds to the inhibitor of apoptosis (IAP) proteins (see Review by Duckett on ...