Whether left ventricular (LV) systolic properties are reduced in diastolic heart failure (DHF) remains controversial, because patients with DHF maintain a normal stroke volume and ejection fraction ...

Because life expectancy and the prevalence of risk factors such as hypertension, obesity and diabetes are rising globally, heart failure (HF) is growing into a major health problem. Impairment of left ...

It is a common perception that approximately 50% of heart failure (HF) patients present with a normal or near-normal left ventricular (LV) ejection fraction ("HF with preserved systolic function"), ...

Background: Prolonged steady state exercise can lead to a decrease in left ventricular (LV) function as well as promote the release of cardiac troponin T (cTnT). There is limited information on the ...

Right ventricular systolic function evaluated through VO2 max is a more accurate measure of functional capacity of persons with heart failure compared with left ventricular systolic function. This ...

8 Research Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool, UK Correspondence to Mathew Wilson, Research Centre for Sport and Exercise Performance, School of ...

Obstructive sleep apnea subjects the failing heart to adverse hemodynamic and adrenergic loads and may thereby contribute to the progression of heart failure. We hypothesized that treatment of ...

The presence of moderate or severe diastolic dysfunction in patients with preserved systolic function independently predicted mortality, a retrospective study determined. After propensity matching to ...

Edgewise Therapeutics (EWTX) announced positive updates from the ongoing CIRRUS-HCM, Phase 2 clinical trial of EDG-7500, a novel oral, selective, ...

Cardiomyopathy is the leading cause of mortality in patients with DMD. Compared with their healthy counterparts, patients with DMD — including those with preserved left ventricular ejection fraction ...