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  1. Hydroxymethylbutyrate (HMB): Benefits, Downsides, and More

    Apr 28, 2021 · HMB is a substance your body produces naturally when it breaks down the amino acid leucine. It may offer benefits as a supplement, possibly helping reduce muscle loss or …

  2. Hydroxymethylbutyrate (HMB): Overview, Uses, Side Effects ...

    It can be found naturally in small amounts in grapefruit, alfalfa, and catfish. It's also naturally made in the body. People use HMB for building muscle or preventing age-related muscle loss.

  3. HMB benefits, dosage, and side effects - Examine

    Sep 4, 2025 · HMB is a metabolite of the essential amino acid leucine that plays an anticatabolic role in muscle tissue. In addition to preventing muscle protein breakdown, HMB may help …

  4. β-Hydroxy β-methylbutyric acid - Wikipedia

    β-Hydroxy β-methylbutyric acid[note 1] (HMB), otherwise known as its conjugate base, β-hydroxy β-methylbutyrate, is a naturally produced substance in humans that is used as a dietary …

  5. Hydroxymethylbutyrate (HMB): Benefits and Side Effects - Health

    Dec 9, 2025 · Hydroxymethylbutyrate (HMB) benefits muscle strength and recovery. It lowers exercise-induced muscle damage and may slow muscle wasting in older adults.

  6. Can Hydroxymethylbutyrate (HMB) Benefit Muscle Growth and ...

    Oct 14, 2025 · HMB is a supplement that may help improve muscle strength and reduce muscle damage. HMB is considered safe for most people, but talk to a healthcare provider before …

  7. What Is HMB (Hydroxymethylbutyrate) Good For, and Does It ...

    HMB has gained popularity recently as a potential muscle builder and workout enhancer. While evidence is still needed, studies show that it may offer a way to prevent muscle loss and aid in …

  8. HMB: What You Should Know from a Dietitian, PhD | GNC

    Feb 18, 2025 · HMB was first discovered in the 90s by Dr. Naji Abumrad and Dr. Steven Nissen. Through their initial research they discovered a metabolite of leucine which activates protein …

  9. HMB Side Effects: What You Need to Know for Muscle Gain

    Aug 6, 2024 · HMB, short for (take a breath) Hydroxymethylbutyrate, is a natural compound your body produces when it breaks down leucine, a critical amino acid for muscle repair and growth.

  10. Experts Explain if HMB Supplements Can Help You Build Muscle

    Apr 30, 2024 · HMB, or hydroxymethylbutyrate, is being touted online as a muscle building supplement. Dietitians explain what HMB is, its health benefits, and risks.